Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 8/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656326 | 0.87 | EPOR (0.43) | EPORGRIK1GRIK2ALOX5PTGS1 | |
| Tert-Butylamine SCHEMBL7112471 | 0.82 | EPOR (0.46) | EPORGRIK1GRIK2ALOX5PTGS1 | |
| SCHEMBL7111053 | 0.77 | PPARA (0.50) | EPORGRIK1GRIK2ALOX5PTGS1 | |
| Tert-Butylamine SCHEMBL7109741 | 0.71 | EPOR (0.43) | EPORPTGS1PTGS2MEN1KMT2A | |
| Tert-Butylamine SCHEMBL7653777 | 0.70 | CYSLTR2 (0.47) | EPORALOX5PTGS1PTGS2ALOX5AP | |
| Tert-Butylamine SCHEMBL7653779 | 0.70 | CYSLTR2 (0.47) | EPORALOX5PTGS1PTGS2ALOX5AP | |
| Tert-Butylamine SCHEMBL7107931 | 0.70 | CACNA1B (0.48) | EPORPPARGMAOB | |
| Tert-Butylamine SCHEMBL7659363 | 0.70 | CACNA1B (0.48) | EPORPPARGMAOB | |
| SCHEMBL7112435 | 0.69 | MAOB (0.51) | EPORALOX5PTGS1PTGS2ALOX5AP | |
| SCHEMBL7105131 | 0.69 | MAOB (0.51) | EPORALOX5PTGS1PTGS2ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335459-B1 | PROSTAGLANDIN I2 RECEPTOR MODULATORS; TREATING TISSUE NECROSIS, PREMATURE UTERINE CONTRACTION, GASTRIC ULCERATION, SEXUAL DYSFUNCTION, MENSTRUAL PAIN AND IMPROPER WOUND HEALING, IMMUNOREGULATION, PLATELET AGGREGATION OR NEUTROPHIL FUNCTION | SYNTEX (U.S.A.) LLC | 2002-01-01 | — | — | US | disclosed |