Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 5/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661832 | 0.87 | EPOR (0.45) | EPORGRIK1GRIK2PPARAPPARG | |
| Tert-Butylamine SCHEMBL7112471 | 0.79 | EPOR (0.46) | EPORGRIK1GRIK2PPARAPPARG | |
| SCHEMBL7109134 | 0.78 | KDM4E (0.44) | EPORTRPM8PPARAPPARG | |
| SCHEMBL7107756 | 0.77 | TRPM8 (0.59) | TRPM8CHRM2CHRM1CHRM3 | |
| SCHEMBL7111053 | 0.74 | PPARA (0.50) | EPORGRIK1GRIK2PPARAPPARG | |
| Tert-Butylamine SCHEMBL7109741 | 0.68 | EPOR (0.43) | EPORCHRM3PTGS1PTGS2 | |
| Tert-Butylamine SCHEMBL7657269 | 0.68 | CYP4F2 (0.39) | EPOR | |
| Tert-Butylamine SCHEMBL7657274 | 0.68 | CYP4F2 (0.39) | EPOR | |
| Tert-Butylamine SCHEMBL7653777 | 0.68 | CYSLTR2 (0.47) | EPORPPARAALOX5ALOX5APPTGS1 | |
| Tert-Butylamine SCHEMBL7653779 | 0.68 | CYSLTR2 (0.47) | EPORPPARAALOX5ALOX5APPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335459-B1 | PROSTAGLANDIN I2 RECEPTOR MODULATORS; TREATING TISSUE NECROSIS, PREMATURE UTERINE CONTRACTION, GASTRIC ULCERATION, SEXUAL DYSFUNCTION, MENSTRUAL PAIN AND IMPROPER WOUND HEALING, IMMUNOREGULATION, PLATELET AGGREGATION OR NEUTROPHIL FUNCTION | SYNTEX (U.S.A.) LLC | 2002-01-01 | — | — | US | disclosed |