Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673154 | 0.86 | HDAC3 (0.46) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL30785121 | 0.85 | KDM4E (0.53) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL321697 | 0.85 | KDM4E (0.53) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL4625651 | 0.83 | SLC6A4 (0.49) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL2908313 | 0.79 | PDE4A (0.50) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL487942 | 0.79 | HSD17B10 (0.62) | — | |
| SCHEMBL1663130 | 0.79 | SLC6A2 (0.46) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL1714408 | 0.79 | SLC6A2 (0.46) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL6912905 | 0.79 | SLC6A2 (0.46) | ALDH1A1MEN1POLBHPGDKMT2A | |
| SCHEMBL31119318 | 0.79 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |