Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 3/20 | 0.47 |
| ▸ | FNTB | P49356 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895134 | 1.00 | LTA4H (0.48) | LTA4HFNTAFNTBNPSR1ALDH1A1 | |
| SCHEMBL6895131 | 1.00 | LTA4H (0.48) | LTA4HFNTAFNTBNPSR1ALDH1A1 | |
| SCHEMBL27559953 | 0.89 | LPAR1 (0.43) | — | |
| SCHEMBL6898194 | 0.89 | LPAR1 (0.43) | — | |
| SCHEMBL6897939 | 0.84 | LPAR1 (0.54) | — | |
| SCHEMBL6898730 | 0.84 | NPC1 (0.45) | ALDH1A1 | |
| SCHEMBL6898735 | 0.84 | NPC1 (0.45) | ALDH1A1 | |
| SCHEMBL6890431 | 0.83 | LPAR1 (0.52) | LTA4HNPSR1CA12CA1CA9 | |
| SCHEMBL6895388 | 0.83 | LPAR1 (0.53) | NPSR1CA12CA1CA9 | |
| SCHEMBL6891317 | 0.83 | LPAR1 (0.53) | NPSR1CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492370-B1 | Urea derivatives and pharmaceutical compositions thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |