Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662427 | 1.00 | PDK2 (0.40) | PDK2PDK4ALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL10909627 | 0.98 | ALDH1A1 (0.39) | PDK2PDK4ALDH1A1GAAMAPT | |
| SCHEMBL9379211 | 0.84 | PDK2 (0.39) | PDK2PDK4ALDH1A1GAAMAPT | |
| SCHEMBL10906348 | 0.84 | PDK2 (0.39) | PDK2PDK4GAAMAPTSMN1; SMN2 | |
| SCHEMBL2001306 | 0.80 | MAPT (0.39) | ALDH1A1GAAMAPTSMN1; SMN2IDO1 | |
| SCHEMBL18463793 | 0.79 | GAA (0.43) | PDK2PDK4ALDH1A1GAAMAPT | |
| SCHEMBL6773255 | 0.77 | KDM4E (0.47) | ALDH1A1GAAMAPTSMN1; SMN2IDO1 | |
| SCHEMBL16464416 | 0.77 | KDM4E (0.47) | ALDH1A1GAAMAPTSMN1; SMN2IDO1 | |
| SCHEMBL7043043 | 0.77 | KDM4E (0.47) | ALDH1A1GAAMAPTSMN1; SMN2IDO1 | |
| SCHEMBL29443040 | 0.77 | KDM4E (0.47) | ALDH1A1GAAMAPTSMN1; SMN2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403561-B1 | DISORDERS ASSOCIATED WITH THE INACTIVATION OR EXCESSIVE DEGRADATION OF CHOLECYSTOKININ; INHIBITING THE ENZYMATIC HYDROLYSIS OF CHOLECYSTOKININ 1-(2(S)-AMINOBUTYRYL)-2(S)-INDOLINECARBOXYLIC ACID | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-06-11 | — | — | US | disclosed |