Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 4/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4941436 | 0.88 | HDAC8 (0.56) | FGFR1FGFR4HDAC8HDAC3HDAC1 | |
| SCHEMBL6086002 | 0.87 | HTR2C (0.55) | HDAC8HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL6191087 | 0.86 | FGFR1 (0.52) | FGFR1FGFR4HDAC8HDAC3HDAC1 | |
| SCHEMBL3785959 | 0.84 | FGFR1 (0.48) | FGFR1FGFR4HDAC8HDAC3HDAC1 | |
| SCHEMBL4943583 | 0.84 | HTR6 (0.58) | FGFR1FGFR4HDAC8HDAC3HDAC1 | |
| SCHEMBL16044140 | 0.84 | FGFR1 (0.51) | FGFR1FGFR4HTR6EPHX2LMNA | |
| SCHEMBL6087674 | 0.83 | MAPT (0.53) | FGFR1FGFR4HDAC8HDAC3HDAC1 | |
| SCHEMBL6087212 | 0.81 | HTR2C (0.51) | HDAC8HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL4937426 | 0.81 | CCR9 (0.55) | FGFR1FGFR4HDAC8HDAC3HDAC1 | |
| SCHEMBL2279750 | 0.81 | HDAC8 (0.64) | FGFR1FGFR4HDAC8HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380249-B1 | HIV integrase inhibitors | MERCK & CO., INC. | 2002-04-30 | — | — | US | disclosed |