SCHEMBL7663191

SCHEMBL7663191

Cc1cc(Cc2cccc(O)c2Cc2cc(C)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 3/20 0.69
CYP2C9 P11712 5/20 0.67
CYP2C19 P33261 5/20 0.67
HIF1A Q16665 4/20 0.67
SMN1; SMN2 Q16637 3/20 0.67
CYP2D6 P10635 1/20 0.60
HSD17B10 Q99714 1/20 0.60
ALDH1A1 P00352 3/20 0.47
CA2 P00918 3/20 0.47
POLB P06746 1/20 0.47
TYR P14679 1/20 0.47
AMY1A P0DUB6 1/20 0.44
TSHR P16473 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
TP53 P04637 2/20 0.38
GABRA1 P14867 2/20 0.37
GABRB2 P47870 2/20 0.37
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
CYP1A2 P05177 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3694841 0.87 HSPA5 (0.71) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL8377430 0.87 HSPA5 (0.75) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
Methane SCHEMBL3694842 0.85 HSPA5 (0.73) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL28672465 0.85 HSPA5 (0.77) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL12733244 0.85 HSPA5 (0.77) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29351672 0.83 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29415372 0.83 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL34162 0.83 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29650132 0.81 HSPA5 (0.66) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL4584268 0.81 HSPA5 (0.66) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1196492-A4 PROCESS FOR MANUFACTURING A BIODEGRADABLE POLYMERIC COMPOSITION PROGRAMABLE LIFE INC (US) 2002-12-18 EP disclosed
EP-1196492-A1 PROCESS FOR MANUFACTURING A BIODEGRADABLE POLYMERIC COMPOSITION Programable Life Inc. (US) 2002-04-17 EP disclosed
WO-2000059996-A1 PROCESS FOR MANUFACTURING A BIODEGRADABLE POLYMERIC COMPOSITION PROGRAMABLE LIFE INC. (US) 2000-10-12 WO disclosed
EP-0363383-A1 DEGRADABLE PLASTICS. EPRON IND LTD (GB) 1990-04-18 EP disclosed
WO-1988009354-A1 DEGRADABLE PLASTICS EPRON INDUSTRIES LIMITED (GB) 1988-12-01 WO disclosed