SCHEMBL4584268

SCHEMBL4584268

Cc1cc(Cc2c(C)ccc(O)c2Cc2cc(C)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.66
CYP2C9 P11712 6/20 0.64
CYP2C19 P33261 6/20 0.64
HIF1A Q16665 5/20 0.64
SMN1; SMN2 Q16637 4/20 0.64
CYP2D6 P10635 3/20 0.61
HSD17B10 Q99714 2/20 0.61
ALDH1A1 P00352 5/20 0.49
TYR P14679 2/20 0.49
CA2 P00918 2/20 0.49
POLB P06746 1/20 0.49
AMY1A P0DUB6 1/20 0.45
TP53 P04637 3/20 0.39
CYP1A2 P05177 4/20 0.38
PTGS2 P35354 2/20 0.36
PTGS1 P23219 1/20 0.36
LMNA P02545 4/20 0.35
ALOX15 P16050 3/20 0.35
NR1I2 O75469 1/20 0.35
MIF P14174 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29650132 1.00 HSPA5 (0.66) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL15939636 0.89 HSPA5 (0.62) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL7663191 0.81 HSPA5 (0.69) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL34162 0.81 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29415372 0.81 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29351672 0.81 HSPA5 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL7749757 0.80 CYP2C19 (0.60) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL722580 0.80 HSPA5 (0.77) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL11247674 0.79 CYP2C9 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2
SCHEMBL29357108 0.79 CYP2C9 (1.00) HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2008544877-A 2008-12-11 JP claimed
EP-1879750-A2 THERMAL IMAGING MEMBERS AND METHODS Zink Imaging, LLC (US) 2008-01-23 EP claimed
WO-2006124560-A2 THERMAL IMAGING MEMBERS AND METHODS ZINK IMAGING, LLC (US) 2006-11-23 WO claimed
CN-110114448-A Lubricating composition with alkylated naphthylamines 路博润公司 2019-08-09 CN disclosed
CN-106164164-A Vinyl chloride resin plasticizer containing non-phthalic acid system ester and the vinyl chloride resin composition containing this plasticizer 新日本理化株式会社 2016-11-23 CN disclosed
US-20080039585-A1 Thermosetting Resin Composition, Thermosetting Film, Cured Product of Those, and Electronic Component JSR CORPORATION (JP) 2008-02-14 US disclosed
EP-1872924-A1 PROCESS FOR PRODUCING CROSSLINKED MOLDED FOAM JSR Corporation (JP) 2008-01-02 EP disclosed
EP-1687278-A1 USE OF 4-CYANO-NAPHTHALENE-1, 8-DICARBOXIMIDE DERIVATIVES AND RELATED COMPOUNDS TO PROTECT ORGANIC MATERIAL FROM THE DAMAGING EFFECTS OF LIGHT BASF AKTIENGESELLSCHAFT (DE) 2006-08-09 EP disclosed
CN-1204183-C thermoplastic elastomer composition with high thermal aging resistance MITSUI CHEMICALS INC (JP) 2005-06-01 CN disclosed
WO-2005047265-A1 USE OF 4-CYANO-NAPHTHALENE-1, 8-DICARBOXIMIDE DERIVATIVES AND RELATED COMPOUNDS TO PROTECT ORGANIC MATERIAL FROM THE DAMAGING EFFECTS OF LIGHT BASF AKTIENGESELLSCHAFT (DE) 2005-05-26 WO disclosed
US-20040067380-A1 Oil-extended 1,2-polybutadiene and method of manufacturing the polybutadiene, and composition and formed product thereof JSR CORPORATION (JP) 2004-04-08 US disclosed
WO-1999023093-A1 2-(2'-HYDROXYPHENYL)BENZOTRIAZOLES USED AS U.V. STABILISERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 1999-05-14 WO disclosed
WO-1999002495-A1 LIGHT-STABILIZING SYNERGIC MIXTURES FOR ORGANIC POLYMERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 1999-01-21 WO disclosed
WO-1998050360-A1 LIGHT-STABILIZED ORGANIC POLYMERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 1998-11-12 WO disclosed
EP-0877053-A2 Rubber composition for a conveyor belt Mitsui Chemicals, Inc. (JP) 1998-11-11 EP disclosed
WO-1998047893-A1 ENAMINE DERIVATIVES FOR USE AS ANTIOXYDANTS FOR POLYMERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 1998-10-29 WO disclosed
EP-0842957-A1 ETHYLENIC RANDOM COPOLYMER, PROCESS FOR PREPARING THE SAME, AND RUBBER COMPOSITION Mitsui Chemicals, Inc. (JP) 1998-05-20 EP disclosed
EP-0217149-B1 POLY(2,2,6,6-TETRAMETHYLPIPERIDYLAMINOSPIROGLYCOLETHER-1,3,5-TRIAZINES) ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1991-01-30 EP disclosed
EP-0209126-A2 Hydrocarbyl(polyphenol)-poly(2,2,6,6-tetramethyl piperidyl-1,3,5-triazines) as stabilizers for synthetic polymer compositions ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1987-01-21 EP disclosed
EP-0095571-A2 Polyhydric alcohol ethers of 2,2,6,6-tetramethyl-4-piperidone ketals and synthetic resin compositions ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1983-12-07 EP disclosed