Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 17/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3975298 | 0.83 | AGTR2 (0.48) | AGTR2AGTR1 | |
| SCHEMBL3903957 | 0.83 | MAS1 (0.56) | AGTR2AGTR1 | |
| SCHEMBL3902365 | 0.76 | MAS1 (0.55) | AGTR2AGTR1 | |
| SCHEMBL3909393 | 0.76 | MAS1 (0.65) | AGTR2AGTR1 | |
| SCHEMBL3973010 | 0.75 | MAS1 (0.57) | AGTR2AGTR1 | |
| SCHEMBL4106849 | 0.75 | MAS1 (0.60) | AGTR2AGTR1 | |
| SCHEMBL4101355 | 0.74 | MAS1 (0.57) | AGTR2AGTR1 | |
| SCHEMBL9585470 | 0.74 | AGTR2 (0.63) | AGTR2AGTR1 | |
| SCHEMBL4110594 | 0.72 | MAS1 (0.58) | AGTR2AGTR1 | |
| SCHEMBL4099345 | 0.71 | MAS1 (0.66) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6429222-B2 | HYPOTENSIVE AGENT, ENDOTHELIAL DAMAGE, ARTERIOSCLEROSIS, ANTIDIABETIC AGENTS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2002-08-06 | — | — | US | disclosed |