Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 3/20 | 0.31 |
| ▸ | MMP2 | P08253 | 3/20 | 0.31 |
| ▸ | MMP3 | P08254 | 3/20 | 0.31 |
| ▸ | MMP8 | P22894 | 3/20 | 0.31 |
| ▸ | MMP13 | P45452 | 3/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897959 | 0.99 | TP53 (0.36) | TP53CHRM3SIGMAR1MCHR1MBOAT4 | |
| SCHEMBL6898851 | 0.99 | TP53 (0.36) | TP53CHRM3SIGMAR1MCHR1MBOAT4 | |
| SCHEMBL6897826 | 0.99 | TP53 (0.36) | TP53CHRM3SIGMAR1MCHR1MBOAT4 | |
| SCHEMBL6895866 | 0.99 | TP53 (0.34) | TP53CHRM3SIGMAR1MCHR1MBOAT4 | |
| SCHEMBL7657328 | 0.99 | TP53 (0.34) | TP53CHRM3SIGMAR1MCHR1MBOAT4 | |
| SCHEMBL6897336 | 0.98 | TP53 (0.34) | TP53CHRM3SIGMAR1MCHR1MBOAT4 | |
| SCHEMBL6891091 | 0.97 | TP53 (0.33) | TP53CHRM3SIGMAR1MCHR1MBOAT4 | |
| SCHEMBL6897036 | 0.96 | LMNA (0.36) | TP53CHRM3SIGMAR1MCHR1MBOAT4 | |
| Cadaverine Tartrate SCHEMBL6891356 | 0.94 | TP53 (0.33) | TP53CHRM3SIGMAR1MCHR1KDM4E | |
| Cadaverine Tartrate SCHEMBL6891161 | 0.94 | TP53 (0.33) | TP53CHRM3SIGMAR1MCHR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492370-B1 | Urea derivatives and pharmaceutical compositions thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |