SCHEMBL766428

SCHEMBL766428

CC(=O)[C@](N)(CCCNC(=N)N)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.36
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KDM4E B2RXH2 1/20 0.31
MAPK1 P28482 1/20 0.31
HIF1A Q16665 1/20 0.31
PAOX Q6QHF9 2/20 0.31
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20524307 1.00 ALOX15 (0.36) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL27751170 0.90 ALOX15 (0.40) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL4670028 0.86 KDM4E (0.33) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL31295699 0.84 ALOX15 (0.33) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL8517227 0.84 FOLH1 (0.39) ALOX15SMN1; SMN2KDM4E
SCHEMBL19305209 0.84 ALOX15 (0.34) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL27083150 0.81 SPHK1 (0.35) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL28216506 0.81 SPHK1 (0.35) ALOX15MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL28459818 0.80 SPHK1 (0.37) ALOX15
SCHEMBL28459817 0.80 SPHK1 (0.37) ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118406439-B Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing 万华化学集团电子材料有限公司 2024-10-18 CN claimed
CN-118406439-A Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing 万华化学集团电子材料有限公司 2024-07-30 CN claimed
CN-119791198-A Application of high-protein duckweed mutant-47 青岛农业大学 2025-04-11 CN disclosed
CN-118406439-B Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing 万华化学集团电子材料有限公司 2024-10-18 CN disclosed
WO-2024206366-A2 GENETICALLY ENCODED SYSTEM FOR QUANTIFYING RUBISCO ACTIVITY IN CATALYZING CARBON FIXATION THE SCRIPPS RESEARCH INSTITUTE (US) 2024-10-03 WO disclosed
CN-118406439-A Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing 万华化学集团电子材料有限公司 2024-07-30 CN disclosed
CN-117740961-A Compound analysis method of liquorice and liquorice probiotics fermentation preparation 北京中医药大学 2024-03-22 CN disclosed
US-11835499-B2 Methods of quantifying methylglyoxal-induced nucleic acid adducts CITY OF HOPE (US) 2023-12-05 US disclosed
US-20220331273-A1 METHODS OF QUANTIFYING N2-(1-CARBOXYETHYL)-2'-DEOXY-GUANOSINE (CEDG) AND SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING CEDG CITY OF HOPE (US) 2022-10-20 US disclosed
EP-4022052-A1 METHODS FOR PRODUCTION OF HUMAN RECOMBINANT ARGINASE 1 AND USES THEREOF Aeglea Biotherapeutics, Inc. (US) 2022-07-06 EP disclosed
US-11266618-B2 Methods of quantifying N2-(1-carboxyethyl)-2′-deoxy-guanosine (CEdG) and synthesis of oligonucleotides containing CEdG CITY OF HOPE (US) 2022-03-08 US disclosed
US-9855233-B2 Methods of quantifying N2-(1-carboxyethyl)-2′-deoxy-guanosine (CEdG) and synthesis of oligonucleotides containing CEdG CITY OF HOPE (US) 2018-01-02 US disclosed
WO-2017027611-A2 BIOMARKERS OF METHYLGLYOXAL AND RELATED METHODS THEREOF THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2017-02-16 WO disclosed
US-20150290156-A1 METHODS OF QUANTIFYING N2-(1-CARBOXYETHYL)-2'-DEOXY-GUANOSINE (CEDG) AND SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING CEDG CITY OF HOPE 2015-10-15 US disclosed
US-8980646-B2 Proteolytic and covalent antibodies PAUL, SUDHIR (US) 2015-03-17 US disclosed
US-20120071559-A1 METHODS OF QUANTIFYING N2-(1-CARBOXYETHYL)-2'-DEOXY-GUANOSINE (CEdG) AND SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING CEdG RAHBAR SAMUEL (US) 2012-03-22 US disclosed
US-20100102218-A1 METHODS OF QUANTIFYING N2-(1-CARBOXYETHYL)-2'-DEOXY-GUANOSINE (CEdG) AND SYNTHESIS OF OLIGONUCLEOTIDES CONTAINING CEdG CITY OF HOPE 2010-04-29 US disclosed
US-20070105092-A1 Proteolytic and covalent antibodies COVALENT BIOSCIENCE INCORPORATED 2007-05-10 US disclosed
EP-1615946-A2 PROTEOLYTIC AND COVALENT ANTIBODIES The University of Texas (US) 2006-01-18 EP disclosed
WO-2004087735-A2 PROTEOLYTIC AND COVALENT ANTIBODIES THE UNIVERSITY OF TEXAS (US) 2004-10-14 WO disclosed