Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598498 | 0.95 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL7637083 | 0.94 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL30078422 | 0.90 | SMN1; SMN2 (0.62) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL6428126 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL12222321 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL30735894 | 0.80 | KDM4E (0.64) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL30078454 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL12818038 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL22654031 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL22654030 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403055-B1 | CARBOXYLATED POLYAMINE COMPOUND | DIBRA S.P.A. (IT) | 2002-06-11 | — | — | US | disclosed |