Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | APAF1 | O14727 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | TACR1 | P25103 | 1/20 | 0.56 |
| ▸ | CDK4 | P11802 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22654030 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL12818038 | 1.00 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL38652174 | 0.87 | KDM4E (0.60) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL25060309 | 0.87 | TACR1 (0.62) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL38660959 | 0.87 | TACR1 (0.56) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL23027210 | 0.87 | TACR1 (0.62) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL31619542 | 0.86 | TACR1 (0.58) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL30735894 | 0.85 | KDM4E (0.64) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL30078422 | 0.85 | SMN1; SMN2 (0.62) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL1162357 | 0.85 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3737663-B1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | UNIV COURT UNIV ST ANDREWS (GB) | 2023-02-22 | — | — | EP | disclosed |
| US-20210053932-A1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2021-02-25 | — | — | US | disclosed |
| EP-3737663-A1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | University Court of The University of St Andrews (GB) | 2020-11-18 | — | — | EP | disclosed |
| CN-111587238-A | Manganese catalyzed ester hydrogenation | 圣安德鲁斯大学董事会 | 2020-08-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053932-A1 | MANGANESE-CATALYSED HYDROGENATION OF ESTERS | ADH5, HDHD5, ADH1A | SMN1; SMN2 300/4885KMT2A 575/4885KDM4E 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.