Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 7/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7662314 | 0.89 | PDGFRB (0.51) | PDGFRBHRH4MEN1KMT2ACDK1 | |
| SCHEMBL7664440 | 0.85 | MEN1 (0.53) | PDGFRBMEN1KMT2AMAPTLMNA | |
| SCHEMBL1029983 | 0.85 | RECQL (0.62) | PDGFRBMEN1KMT2AMAPTLMNA | |
| SCHEMBL1029982 | 0.78 | PDGFRB (0.61) | PDGFRBMEN1KMT2AMAPTLMNA | |
| SCHEMBL38942 | 0.76 | HRH4 (0.85) | PDGFRBHRH4CDK1LMNAHTT | |
| Hydrochloric Acid SCHEMBL7662308 | 0.74 | PDGFRB (0.51) | PDGFRBMEN1KMT2AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL1031470 | 0.74 | PDGFRB (0.59) | PDGFRBHRH4MAPTLMNAKIT | |
| SCHEMBL1032705 | 0.73 | PDGFRB (0.62) | PDGFRBHRH4MAPTGAAALDH1A1 | |
| SCHEMBL7659416 | 0.71 | PDGFRB (1.00) | PDGFRB | |
| SCHEMBL30945086 | 0.70 | PDGFRB (0.62) | PDGFRBMEN1KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423716-B1 | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-07-23 | — | — | US | disclosed |
| EP-1067123-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |