Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 13/20 | 0.61 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.57 |
| ▸ | KIT | P10721 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1031469 | 0.88 | PDGFRB (0.61) | PDGFRBPDGFRAKITMEN1KMT2A | |
| SCHEMBL7664440 | 0.87 | MEN1 (0.53) | PDGFRBPDGFRAKITMEN1KMT2A | |
| SCHEMBL1032702 | 0.86 | PDGFRB (0.65) | PDGFRBPDGFRAKITGAAMAPT | |
| SCHEMBL1029983 | 0.85 | RECQL (0.62) | PDGFRBPDGFRAKITMEN1KMT2A | |
| SCHEMBL1028115 | 0.82 | KIT (0.66) | PDGFRBPDGFRAKITLMNAGAA | |
| SCHEMBL2912785 | 0.81 | PDGFRB (0.78) | PDGFRBPDGFRAKITMEN1KMT2A | |
| SCHEMBL29230275 | 0.80 | PDGFRB (0.62) | PDGFRBPDGFRAKITMEN1KMT2A | |
| SCHEMBL30945086 | 0.80 | PDGFRB (0.62) | PDGFRBPDGFRAKITMEN1KMT2A | |
| SCHEMBL5849590 | 0.80 | AKT1 (0.53) | KITMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL7664448 | 0.78 | PDGFRB (0.55) | PDGFRBPDGFRAKITMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067123-B1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KIRIN CO LTD (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-6423716-B1 | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-07-23 | — | — | US | disclosed |
| EP-1067123-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |