Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664609 | 1.00 | PTAFR (0.80) | PTAFR | |
| SCHEMBL7664613 | 1.00 | PTAFR (0.80) | PTAFR | |
| SCHEMBL10429013 | 0.91 | PTAFR (0.69) | PTAFR | |
| SCHEMBL7695791 | 0.91 | PTAFR (0.77) | PTAFR | |
| SCHEMBL7133900 | 0.91 | PTAFR (0.77) | PTAFR | |
| SCHEMBL7594055 | 0.91 | PTAFR (0.77) | PTAFR | |
| Dimethylamine SCHEMBL10459942 | 0.90 | PTAFR (0.65) | PTAFR | |
| SCHEMBL10429004 | 0.89 | PTAFR (0.63) | PTAFR | |
| SCHEMBL10429003 | 0.89 | PTAFR (0.63) | PTAFR | |
| SCHEMBL10429002 | 0.89 | PTAFR (0.63) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749306-A4 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR, INFLAMMATORY AND IMMUNE DISORDERS | CYTOMED INC (US) | 1997-04-16 | — | — | EP | claimed |
| EP-0749306-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR, INFLAMMATORY AND IMMUNE DISORDERS | CYTOMED, INC. (US) | 1996-12-27 | — | — | EP | claimed |
| US-5463083-A | Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders | CYTOMED, INC. (US) | 1995-10-31 | — | — | US | claimed |
| WO-1995018610-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR, INFLAMMATORY AND IMMUNE DISORDERS | CYTOMED, INC. (US) | 1995-07-13 | — | — | WO | claimed |
| US-6420392-B1 | PAF RECEPTOR ANTAGONISTS AND/OR BY INHIBITING THE ENZYME 5-LIPOXYGENASE. | MILLENNIUM PHARMACEUTICALS, INC. | 2002-07-16 | — | — | US | disclosed |
| US-5741809-A | Compounds and methods for the treatment of cardiovascular inflammatory and immune disorders | CYTOMED, INC. (US) | 1998-04-21 | — | — | US | disclosed |
| EP-0749306-A4 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR, INFLAMMATORY AND IMMUNE DISORDERS | CYTOMED INC (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0749306-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR, INFLAMMATORY AND IMMUNE DISORDERS | CYTOMED, INC. (US) | 1996-12-27 | — | — | EP | disclosed |
| EP-0402151-B1 | New 2, 5-diaryl tetrahydrofurans and analogs thereof as paf antagonists | MERCK & CO INC (US) | 1996-02-07 | — | — | EP | disclosed |
| US-5463083-A | Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders | CYTOMED, INC. (US) | 1995-10-31 | — | — | US | disclosed |
| WO-1995018610-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CARDIOVASCULAR, INFLAMMATORY AND IMMUNE DISORDERS | CYTOMED, INC. (US) | 1995-07-13 | — | — | WO | disclosed |
| US-5114961-A | 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists | MERCK & CO., INC. (US) | 1992-05-19 | — | — | US | disclosed |
| US-4996203-A | Platelet-activating factor antagonists | MERCK & CO., INC. (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0402150-A1 | New 2,5-diaryl tetrahydrofurans and analogs therof as PAF antagonists | MERCK & CO. INC. (US) | 1990-12-12 | — | — | EP | disclosed |
| EP-0402151-A1 | New 2, 5-diaryl tetrahydrofurans and analogs thereof as paf antagonists | MERCK & CO. INC. (US) | 1990-12-12 | — | — | EP | disclosed |
| US-4977146-A | ANTICOAGULANT | MERCK & CO., INC. (US) | 1990-12-11 | — | — | US | disclosed |