Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | MC3R | P41968 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664796 | 1.00 | PGR (0.30) | PGRADORA3ADRA2CSLC6A2HTR2B | |
| SCHEMBL7664789 | 1.00 | PGR (0.30) | PGRADORA3ADRA2CSLC6A2HTR2B | |
| SCHEMBL7671627 | 0.92 | — | — | |
| SCHEMBL7671619 | 0.92 | — | — | |
| SCHEMBL7671624 | 0.92 | — | — | |
| SCHEMBL7668019 | 0.92 | — | — | |
| SCHEMBL7668024 | 0.92 | — | — | |
| SCHEMBL7665603 | 0.92 | TBXA2R (0.37) | — | |
| SCHEMBL7665591 | 0.92 | TBXA2R (0.37) | — | |
| SCHEMBL7869363 | 0.92 | TBXA2R (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359181-B1 | THERAPY FOR VISION DEFECTS | ALLERGAN SALES, INC. | 2002-03-19 | — | — | US | disclosed |
| US-6307092-B1 | POTENT OCULAR HYPOTENSIVES AND ARE PARTICULARLY SUITED FOR THE MANAGEMENT OF GLAUCOMA. | ALLERGAN SALES, INC. | 2001-10-23 | — | — | US | disclosed |
| US-6248783-B1 | GLAUCOMA THERAPY | ALLERGAN SALES, INC. | 2001-06-19 | — | — | US | disclosed |