SCHEMBL7664804

SCHEMBL7664804

CCCC(COc1c(Cl)cc(Cl)cc1Cl)N[C]=O

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
CNR2 P34972 1/20 0.32
SCN4A P35499 2/20 0.31
AHR P35869 1/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
CNR1 P21554 1/20 0.31
POLB P06746 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10445479 0.72 SCN4A (0.42) TSHRSCN4AMAPTTDP1
SCHEMBL3689772 0.70 CNR1 (0.37) CNR2AHRTAS1R3TAS1R1CNR1
SCHEMBL675217 0.69 AHR (0.53) AHR
SCHEMBL1279332 0.68 AHR (0.37) TSHRCNR2AHRTAS1R3TAS1R1
SCHEMBL293424 0.68 TAS1R3 (0.33) TDP1TAS1R3TAS1R1
SCHEMBL10673301 0.67 TSHR (0.38) TSHRSCN4ACYP1A2CYP2D6POLB
SCHEMBL13261204 0.65 MAPT (0.49) AHRMAPTTDP1POLBALDH1A1
SCHEMBL12681500 0.64 CYP1A2 (0.50) TSHRCYP1A2CYP2D6MAPTTDP1
SCHEMBL270980 0.64
SCHEMBL8606655 0.64 SCN4A (0.48) TSHRSCN4ACYP1A2CYP2D6MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002067679-A1 FUNGICIDAL MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2002-09-06 WO disclosed