Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675670 | 1.00 | CCR5 (0.68) | CCR5 | |
| SCHEMBL7673931 | 1.00 | CCR5 (0.68) | CCR5 | |
| SCHEMBL7666767 | 1.00 | CCR5 (0.68) | CCR5 | |
| SCHEMBL7665218 | 1.00 | CCR5 (0.68) | CCR5 | |
| SCHEMBL7668948 | 0.91 | CCR5 (0.70) | CCR5 | |
| SCHEMBL7675636 | 0.91 | CCR5 (0.70) | CCR5 | |
| SCHEMBL7668946 | 0.91 | CCR5 (0.70) | CCR5 | |
| SCHEMBL7666851 | 0.90 | CCR5 (0.72) | CCR5 | |
| SCHEMBL7667172 | 0.90 | CCR5 (0.72) | CCR5 | |
| SCHEMBL7666857 | 0.90 | CCR5 (0.72) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500844-B1 | PIPERIDINYL-1-METHYLCYCLOPENTANES AND STEREOISOMERS, USED AS ANTIINFLAMMATORY AND PROPHYLACTIC AGENTS AGAINST ALLERGIC RHINITIS, DERMATITIS, VISION DEFECTS, ASTHMA, ATHRITIS AND FOR PREVENTION OR DELAY OF AQUIRED IMMUNE DIFICIENCY SYNDROME | MERCK & CO., INC. | 2002-12-31 | — | — | US | disclosed |