⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782922 | 0.57 | — | — | |
| SCHEMBL22275395 | 0.57 | SORD (0.31) | — | |
| SCHEMBL23277314 | 0.57 | AOC3 (0.40) | — | |
| SCHEMBL9438068 | 0.56 | — | — | |
| SCHEMBL23277243 | 0.56 | — | — | |
| SCHEMBL23295298 | 0.56 | — | — | |
| SCHEMBL17791788 | 0.53 | NOTUM (0.32) | — | |
| SCHEMBL1244232 | 0.53 | NOTUM (0.32) | — | |
| SCHEMBL23277296 | 0.52 | — | — | |
| SCHEMBL3875958 | 0.49 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355638-B1 | COGNITION ACTIVATORS | MERCK SHARP & DOHME LTD. (GB) | 2002-03-12 | — | — | US | disclosed |