Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.43 |
| ▸ | PPARG | P37231 | 17/20 | 0.43 |
| ▸ | PPARD | Q03181 | 17/20 | 0.43 |
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671701 | 0.92 | PPARA (0.43) | PPARAPPARGPPARDPDE5A | |
| SCHEMBL7663368 | 0.89 | PPARA (0.40) | PPARAPPARGPPARD | |
| SCHEMBL7669108 | 0.86 | PPARG (0.39) | PPARAPPARGPPARD | |
| SCHEMBL5211567 | 0.84 | PPARA (0.43) | PPARAPPARGPPARDPDE5A | |
| SCHEMBL7670010 | 0.81 | PPARA (0.40) | PPARAPPARGPPARDPDE5A | |
| SCHEMBL7668178 | 0.79 | PPARG (0.39) | PPARAPPARGPPARD | |
| SCHEMBL5211565 | 0.78 | PPARG (0.61) | PPARAPPARGPPARD | |
| SCHEMBL7454425 | 0.77 | PPARG (0.43) | PPARAPPARGPPARDPDE5A | |
| SCHEMBL5205501 | 0.77 | PPARA (0.57) | PPARAPPARGPPARD | |
| SCHEMBL7464894 | 0.77 | PPARG (0.42) | PPARAPPARGPPARDPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399640-B1 | ANTIDIABETIC AGENTS; ANTICHOLESTEROL AGENTS | MERCK & CO., INC. | 2002-06-04 | — | — | US | claimed |