Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.39 |
| ▸ | PPARD | Q03181 | 12/20 | 0.39 |
| ▸ | PPARA | Q07869 | 12/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669108 | 0.92 | PPARG (0.39) | PPARGPPARDPPARAKCNA3CYSLTR2 | |
| SCHEMBL7671701 | 0.86 | PPARA (0.43) | PPARGPPARDPPARA | |
| SCHEMBL7459824 | 0.85 | PDE5A (0.35) | PPARGPPARDPPARA | |
| SCHEMBL5211391 | 0.83 | PPARG (0.40) | PPARGPPARDPPARAKCNA3CYSLTR2 | |
| SCHEMBL5204448 | 0.82 | PPARG (0.40) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL7665347 | 0.79 | PPARA (0.43) | PPARGPPARDPPARA | |
| SCHEMBL5211380 | 0.77 | PPARG (0.62) | PPARGPPARDPPARA | |
| SCHEMBL5208981 | 0.77 | PPARG (0.51) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL7670010 | 0.76 | PPARA (0.40) | PPARGPPARDPPARA | |
| SCHEMBL7461206 | 0.75 | PPARG (0.39) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399640-B1 | ANTIDIABETIC AGENTS; ANTICHOLESTEROL AGENTS | MERCK & CO., INC. | 2002-06-04 | — | — | US | claimed |
| US-6399640-B1 | ANTIDIABETIC AGENTS; ANTICHOLESTEROL AGENTS | MERCK & CO., INC. | 2002-06-04 | — | — | US | disclosed |