Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138882 | 0.92 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL24488930 | 0.86 | ALDH1A1 (0.74) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7147094 | 0.83 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7670139 | 0.82 | MAPT (0.62) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7003377 | 0.81 | ALDH1A1 (0.80) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL6994846 | 0.81 | KDM4E (0.60) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7673387 | 0.81 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7145607 | 0.80 | MAPT (0.61) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL24489106 | 0.79 | ALDH1A1 (0.76) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL5096639 | 0.77 | ALDH1A1 (0.73) | MEN1KMT2AALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | claimed |