Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 8/20 | 0.62 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 9/20 | 0.61 |
| ▸ | GSK3A | P49840 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | CLK2 | P49760 | 2/20 | 0.55 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.55 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656126 | 0.89 | MAPT (0.63) | PDGFRAGRIK1KDRGSK3AGSK3B | |
| SCHEMBL1147612 | 0.85 | NR4A2 (0.57) | PDGFRA | |
| SCHEMBL7663190 | 0.84 | GAK (0.71) | PDGFRAKDRGSK3AGSK3BKMT2A | |
| SCHEMBL7370903 | 0.83 | HTR2C (0.70) | PDGFRAKDRGSK3AGSK3BMAPT | |
| SCHEMBL21121632 | 0.83 | MAPT (0.69) | PDGFRAKDRMAPTKMT2APOLB | |
| Hydrochloric Acid SCHEMBL7658423 | 0.81 | HTR2C (0.67) | PDGFRAKDRGSK3AGSK3BMAPT | |
| SCHEMBL27953778 | 0.77 | CYP1A2 (0.59) | GSK3AGSK3BMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7492018 | 0.77 | KDR (0.87) | PDGFRAKDR | |
| SCHEMBL31067639 | 0.77 | PDGFRA (1.00) | PDGFRAKDR | |
| SCHEMBL3962093 | 0.77 | GRIK1 (1.00) | GRIK1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | claimed |
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | disclosed |