Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666364 | 1.00 | ADRA1A (0.55) | ADRA1ANPY5RTP53NOTUMBCHE | |
| SCHEMBL7660687 | 0.91 | ADRA1A (0.45) | ADRA1ANPY5RTP53NOTUMBCHE | |
| Hydrochloric Acid SCHEMBL7660897 | 0.89 | ADRA1A (0.50) | ADRA1ANPY5RTP53NOTUMHCRTR1 | |
| Hydrochloric Acid SCHEMBL7660892 | 0.89 | ADRA1A (0.50) | ADRA1ANPY5RTP53NOTUMHCRTR1 | |
| SCHEMBL7670537 | 0.89 | NPY5R (0.46) | ADRA1ANPY5RTP53BCHEACHE | |
| SCHEMBL7670540 | 0.89 | NPY5R (0.46) | ADRA1ANPY5RTP53BCHEACHE | |
| Hydrochloric Acid SCHEMBL7662895 | 0.88 | ADRA1A (0.49) | ADRA1ANPY5RTP53NOTUMHTR3A | |
| SCHEMBL7660690 | 0.88 | NPY5R (0.44) | ADRA1ANPY5RTP53NOTUMBCHE | |
| SCHEMBL7660679 | 0.88 | NPY5R (0.44) | ADRA1ANPY5RTP53NOTUMBCHE | |
| SCHEMBL7666705 | 0.88 | NPY5R (0.47) | ADRA1ANPY5RTP53BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355641-B1 | HYPOTENSIVE AGENTS AND WOUND HEALING AGENTS | SYNTEX (U.S.A.) LLC | 2002-03-12 | — | — | US | claimed |
| WO-2000055143-A1 | OXAZOLONE DERIVATIVES AND THEIR USE AS ALPHA-1 ADRENORECEPTOR MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-09-21 | — | — | WO | claimed |
| US-6355641-B1 | HYPOTENSIVE AGENTS AND WOUND HEALING AGENTS | SYNTEX (U.S.A.) LLC | 2002-03-12 | — | — | US | disclosed |
| WO-2000055143-A1 | OXAZOLONE DERIVATIVES AND THEIR USE AS ALPHA-1 ADRENORECEPTOR MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2000-09-21 | — | — | WO | disclosed |