Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.55 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.54 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27893917 | 0.98 | GABBR2 (0.53) | GABBR2GABBR1TAAR1HTR2ACHRNB2 | |
| Hydrochloric Acid SCHEMBL28801403 | 0.98 | GABBR2 (0.53) | GABBR2GABBR1TAAR1HTR2ACHRNB2 | |
| SCHEMBL1415533 | 0.85 | TAAR1 (0.43) | GABBR2GABBR1TAAR1HTR2AHRH1 | |
| SCHEMBL1539105 | 0.85 | TAAR1 (0.65) | GABBR2GABBR1TAAR1HTR2ACHRNB2 | |
| Hydrochloric Acid SCHEMBL10676327 | 0.82 | TAAR1 (0.62) | GABBR2GABBR1TAAR1HTR2ACHRNB2 | |
| SCHEMBL9137323 | 0.81 | HRH1 (0.62) | GABBR2GABBR1TAAR1HTR2ACHRNB2 | |
| SCHEMBL13885260 | 0.81 | HRH1 (0.44) | GABBR2GABBR1TAAR1HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL14833272 | 0.80 | HRH1 (0.56) | GABBR2GABBR1TAAR1HTR2AHRH1 | |
| SCHEMBL12341793 | 0.80 | HTR2A (0.40) | GABBR2GABBR1TAAR1HTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL4696708 | 0.79 | HRH1 (0.60) | GABBR2GABBR1TAAR1HTR2ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102976954-A | Preparation method of chiral 2-fluoromethyl phenyl ethylamine | WUXI APPTEC CO LTD | 2013-03-20 | — | — | CN | claimed |
| CN-102976954-A | Preparation method of chiral 2-fluoromethyl phenyl ethylamine | WUXI APPTEC CO LTD | 2013-03-20 | — | — | CN | disclosed |
| CN-1147489-C | New bicyclo aminopyrazineone compound, its producing process and medical composition containing them | ɪά��ʵ���� | 2004-04-28 | — | — | CN | disclosed |
| EP-1230218-A1 | POSITIVE MODULATORS OF NICOTINIC RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001032622-A1 | POSITIVE MODULATORS OF NICOTINIC RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-05-10 | — | — | WO | disclosed |
| CN-1277198-A | New bicyclo aminopyrazineone compound, its producing process and medical composition containing them | ADIR (FR) | 2000-12-20 | — | — | CN | disclosed |