Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | HCK | P08631 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3774414 | 0.94 | USP2 (0.32) | — | |
| SCHEMBL7666616 | 0.92 | CHEK1 (0.31) | CHEK1IKBKBMAPK13DAPK3JAK2 | |
| SCHEMBL149286 | 0.85 | USP2 (0.32) | — | |
| SCHEMBL7661789 | 0.85 | CCNE2 (0.30) | CDK2 | |
| SCHEMBL2531354 | 0.80 | LMNA (0.38) | PDE1APDE1BPDE1C | |
| SCHEMBL8691661 | 0.78 | — | — | |
| SCHEMBL7661801 | 0.77 | HPGD (0.32) | CDK2 | |
| SCHEMBL28350069 | 0.76 | CACNA1H (0.32) | — | |
| SCHEMBL8693371 | 0.76 | GRM4 (0.31) | — | |
| SCHEMBL8693411 | 0.76 | GRM4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6352958-B1 | PRE- AND POST-EMERGENCE HERBICIDES | FMC CORPORATION | 2002-03-05 | — | — | US | disclosed |
| US-6077812-A | 4-OR 7-(2,6-DI(OXO),3-SUBSTITUTED, 4-TRIFLUOROMETHYL-1,2,3, 6-TETRAHYDROPYRIMIDIN-1-YL)BENZIMIDAZOLES; CONTROLLING WEEDS | FMC CORPORATION (US) | 2000-06-20 | — | — | US | disclosed |
| EP-0968207-A1 | CYCLOIMIDO-SUBSTITUTED BENZOFUSED HETEROCYCLIC HERBICIDES | FMC CORPORATION (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998038188-A1 | CYCLOIMIDO-SUBSTITUTED BENZOFUSED HETEROCYCLIC HERBICIDES | FMC CORPORATION (US) | 1998-09-03 | — | — | WO | disclosed |