Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 3/20 | 0.40 |
| ▸ | CDK7 | P50613 | 2/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.40 |
| ▸ | CCNH | P51946 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.31 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.31 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994176 | 0.99 | CDK9 (0.41) | CDK9CDK7CCNT1CCNHPIK3CG | |
| SCHEMBL7000703 | 0.96 | CDK9 (0.41) | CDK9CDK7CCNT1CCNHPIK3CG | |
| SCHEMBL7143929 | 0.94 | CDK9 (0.41) | CDK9CDK7CCNT1CCNHPIK3CG | |
| SCHEMBL7001680 | 0.90 | CDK9 (0.42) | CDK9CDK7CCNT1CCNHPIK3CG | |
| SCHEMBL7001175 | 0.86 | CDK9 (0.39) | CDK9CDK7CCNT1CCNHPIK3CG | |
| SCHEMBL7003532 | 0.86 | CDK9 (0.42) | CDK9CDK7CCNT1CCNHPIK3CG | |
| SCHEMBL7004329 | 0.85 | CDK9 (0.39) | CDK9CDK7CCNT1CCNHPIK3CG | |
| SCHEMBL7005128 | 0.82 | CDK7 (0.40) | CDK9CDK7CCNT1CCNHPIK3CG | |
| SCHEMBL6997870 | 0.82 | CDK7 (0.36) | CDK9CDK7CCNT1CCNHPIK3CG | |
| SCHEMBL7000284 | 0.81 | CDK9 (0.39) | CDK9CDK7CCNT1CCNHPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372749-B1 | PHARMACOLOGICAL EFFECTS SUCH AS ANALGESIC ACTION, INHIBITORY EFFECT ON NITROGEN MONOXIDE SYNTHETASE AND THE LIKE AND ARE USEFUL AS ANALGESICS. | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2002-04-16 | — | — | US | disclosed |