Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.79 |
| ▸ | FLT1 | P17948 | 20/20 | 0.79 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116866 | 0.90 | EGFR (0.81) | EGFRFLT1KDR | |
| SCHEMBL7124130 | 0.88 | EGFR (1.00) | EGFRFLT1KDR | |
| SCHEMBL7123723 | 0.88 | EGFR (1.00) | EGFRFLT1KDR | |
| SCHEMBL7115633 | 0.87 | EGFR (0.82) | EGFRFLT1KDR | |
| SCHEMBL7126972 | 0.86 | EGFR (0.97) | EGFRFLT1KDR | |
| SCHEMBL7118299 | 0.86 | EGFR (1.00) | EGFRFLT1KDR | |
| SCHEMBL7130002 | 0.86 | EGFR (0.84) | EGFRFLT1KDR | |
| SCHEMBL7127726 | 0.85 | EGFR (0.80) | EGFRFLT1KDR | |
| SCHEMBL7123628 | 0.85 | EGFR (0.80) | EGFRFLT1KDR | |
| SCHEMBL8157768 | 0.85 | EGFR (0.71) | EGFRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492383-B1 | Thienopyrimidine and thienopyridine derivatives useful as anticancer agents | PFIZER INC. | 2002-12-10 | — | — | US | claimed |