Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.71 |
| ▸ | FLT1 | P17948 | 19/20 | 0.71 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160355 | 0.90 | FLT1 (0.67) | EGFRFLT1PRKCQPRKCD | |
| SCHEMBL7127760 | 0.88 | EGFR (0.73) | EGFRFLT1PRKCQPRKCD | |
| SCHEMBL7126230 | 0.88 | EGFR (0.79) | EGFRFLT1PRKCQPRKCD | |
| SCHEMBL7668263 | 0.85 | EGFR (0.79) | EGFRFLT1 | |
| SCHEMBL7127750 | 0.84 | EGFR (0.76) | EGFRFLT1PRKCQPRKCD | |
| SCHEMBL7119457 | 0.83 | EGFR (1.00) | EGFRFLT1PRKCQPRKCD | |
| SCHEMBL7126184 | 0.83 | EGFR (0.78) | EGFRFLT1PRKCQPRKCD | |
| SCHEMBL7127685 | 0.80 | EGFR (1.00) | EGFRFLT1 | |
| SCHEMBL7127504 | 0.79 | EGFR (0.72) | EGFRFLT1PRKCQPRKCD | |
| SCHEMBL7127001 | 0.79 | EGFR (0.77) | EGFRFLT1PRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028964-A1 | THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | Pfizer Products Inc. (US) | 2000-08-23 | — | — | EP | claimed |
| WO-1999024440-A1 | THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER PRODUCTS INC. (US) | 1999-05-20 | — | — | WO | claimed |
| EP-1028964-A1 | THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | Pfizer Products Inc. (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024440-A1 | THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER PRODUCTS INC. (US) | 1999-05-20 | — | — | WO | disclosed |