Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.73 |
| ▸ | MET | P08581 | 1/20 | 0.63 |
| ▸ | AXL | P30530 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 8/20 | 0.52 |
| ▸ | DRD2 | P14416 | 6/20 | 0.52 |
| ▸ | DRD3 | P35462 | 6/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3888485 | 0.86 | GPR84 (0.69) | GPR84METAXLMTNR1ADRD4 | |
| SCHEMBL27911675 | 0.85 | GPR84 (1.00) | GPR84METAXLMTNR1ADRD4 | |
| SCHEMBL2217980 | 0.83 | GPR84 (0.76) | GPR84METAXLMTNR1ADRD4 | |
| SCHEMBL31385845 | 0.81 | GPR84 (0.73) | GPR84METAXLMTNR1ADRD4 | |
| SCHEMBL2692513 | 0.81 | GPR84 (0.73) | GPR84METAXLMTNR1ADRD4 | |
| SCHEMBL7010590 | 0.81 | GPR84 (0.73) | GPR84METAXLMTNR1ADRD4 | |
| SCHEMBL3934105 | 0.81 | GPR84 (0.73) | GPR84METAXLMTNR1ADRD4 | |
| SCHEMBL6219244 | 0.81 | GPR84 (0.73) | GPR84METAXLMTNR1ADRD4 | |
| SCHEMBL1836680 | 0.81 | GPR84 (0.73) | GPR84METAXLMTNR1ADRD4 | |
| SCHEMBL4833176 | 0.81 | GPR84 (0.67) | GPR84METAXLMTNR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414003-B1 | ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| US-6169102-B1 | ANTI-HELICOBACTER PYLORI AGENT COMPRISING AN OXAZOLIN-4-ONE DERIVATIVE USEFUL AS A THERAPEUTIC AGENT FOR GASTRIC AND DUODENAL ULCER | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-02 | — | — | US | disclosed |