Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6913123 | 0.85 | TRIM24 (0.35) | SLC6A4SLC6A2TRIM33TRIM24CYP19A1 | |
| SCHEMBL7134263 | 0.79 | HRH3 (0.46) | SLC6A4SLC6A2OPRD1USP2CYP19A1 | |
| Hydrochloric Acid SCHEMBL7484921 | 0.78 | HRH3 (0.45) | SLC6A4SLC6A2OPRD1USP2CYP19A1 | |
| SCHEMBL7658608 | 0.76 | FNTA (0.52) | TSHRSMN1; SMN2 | |
| SCHEMBL444433 | 0.75 | FNTA (0.50) | — | |
| SCHEMBL7837592 | 0.75 | FNTA (0.45) | SLC6A4SLC6A2TRIM33 | |
| Hydrochloric Acid SCHEMBL8161653 | 0.74 | FNTA (0.49) | — | |
| Hydrochloric Acid SCHEMBL7834494 | 0.74 | FNTA (0.44) | SLC6A4SLC6A2TRIM33 | |
| SCHEMBL7528341 | 0.74 | FNTA (0.59) | SLC6A4SLC6A2HRH2HRH1HRH3 | |
| Hydrochloric Acid SCHEMBL7628308 | 0.73 | FNTA (0.41) | SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335343-B1 | IMIDAZOL-5-YLALKYLPIPERIZINE DERIVATIVES; ANTICARCINOGENIC AGENTS | MERCK & CO., INC. | 2002-01-01 | — | — | US | disclosed |