Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 9/20 | 0.45 |
| ▸ | FNTB | P49356 | 9/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7834494 | 0.99 | FNTA (0.44) | FNTAFNTBPGGT1BNR1H4TRIM33 | |
| SCHEMBL444433 | 0.76 | FNTA (0.50) | FNTAFNTBPGGT1B | |
| SCHEMBL7837588 | 0.75 | FNTA (0.35) | FNTAFNTBPGGT1BNR1H4TRIM33 | |
| Hydrochloric Acid SCHEMBL8161653 | 0.75 | FNTA (0.49) | FNTAFNTBPGGT1B | |
| SCHEMBL7668376 | 0.75 | SLC6A4 (0.44) | TRIM33SLC6A2SLC6A4 | |
| SCHEMBL7836006 | 0.74 | FNTA (0.53) | FNTAFNTBPGGT1B | |
| SCHEMBL6913123 | 0.74 | TRIM24 (0.35) | FNTAFNTBTRIM33SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL7838781 | 0.73 | FNTA (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL7453424 | 0.71 | FNTA (0.53) | FNTAFNTBPGGT1BSLC6A2 | |
| SCHEMBL5759105 | 0.71 | KCNH2 (0.37) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891350-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-01-17 | — | — | EP | claimed |
| EP-0891350-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | claimed |
| WO-1997036889-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | claimed |
| EP-0891350-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-01-17 | — | — | EP | disclosed |
| EP-0891350-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036889-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |