Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700976 | 0.75 | CCKBR (0.39) | CCKBR | |
| SCHEMBL9700947 | 0.74 | CCKBR (0.52) | CCKBR | |
| SCHEMBL7663025 | 0.72 | CCKBR (0.71) | CCKBR | |
| SCHEMBL9400038 | 0.71 | CCKBR (0.51) | CCKBR | |
| SCHEMBL9399753 | 0.70 | CYP3A4 (0.45) | — | |
| SCHEMBL7668755 | 0.70 | CCKBR (0.88) | CCKBR | |
| SCHEMBL6895794 | 0.70 | CCKBR (0.88) | CCKBR | |
| SCHEMBL7820435 | 0.68 | CCKBR (0.63) | CCKBR | |
| SCHEMBL6896752 | 0.67 | CCKBR (0.73) | CCKBR | |
| SCHEMBL7665345 | 0.67 | CCKBR (0.73) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003721-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | claimed |
| US-6492531-B1 | THE INVENTION CONCERNS CHOLECYSTOKININ (CCK) ANTAGONISTS USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS. ESPECIALLY USEFUL ARE CCK.SUB.B ANTAGONISTS SUCH AS CI-988. | WARNER-LAMBERT COMPANY | 2002-12-10 | — | — | US | disclosed |
| WO-1993003721-A1 | CHOLECYSTOKININ ANTAGONISTS USEFUL FOR TREATING DEPRESSION | WARNER-LAMBERT COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |