Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663834 | 0.92 | CCR5 (0.45) | CCR5 | |
| SCHEMBL7666514 | 0.88 | CCR5 (0.66) | CCR5 | |
| Hydrochloric Acid SCHEMBL7666561 | 0.88 | CCR5 (0.66) | CCR5 | |
| Hydrochloric Acid SCHEMBL7673021 | 0.85 | CCR5 (0.54) | CCR5 | |
| SCHEMBL7667436 | 0.82 | CCR5 (0.56) | CCR5 | |
| SCHEMBL7662163 | 0.81 | CCR5 (0.58) | CCR5 | |
| SCHEMBL7666439 | 0.81 | CCR5 (0.62) | CCR5 | |
| SCHEMBL7666965 | 0.80 | CCR5 (0.52) | CCR5 | |
| Hydrochloric Acid SCHEMBL7667305 | 0.78 | CCR5 (0.48) | CCR5 | |
| SCHEMBL6630771 | 0.76 | CCR5 (0.78) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472410-B1 | N-cyclopentyl modulators of chemokine receptor activity | MERCK & CO., INC. | 2002-10-29 | — | — | US | disclosed |