Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 3/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RARG | P13631 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668649 | 1.00 | RARA (0.39) | RARARARBRARGMAPTALDH1A1 | |
| SCHEMBL7669401 | 0.83 | HDAC1 (0.43) | RARARARBRARGMAPTALDH1A1 | |
| SCHEMBL7665263 | 0.83 | HDAC1 (0.43) | RARARARBRARGMAPTALDH1A1 | |
| SCHEMBL7673001 | 0.83 | RARA (0.38) | RARARARBRARGALDH1A1HPGD | |
| SCHEMBL7673007 | 0.83 | RARA (0.38) | RARARARBRARGALDH1A1HPGD | |
| SCHEMBL7669871 | 0.82 | HDAC1 (0.40) | RARARARBRARGMAPTALDH1A1 | |
| SCHEMBL7662574 | 0.82 | HDAC1 (0.40) | RARARARBRARGMAPTALDH1A1 | |
| SCHEMBL7662581 | 0.82 | HDAC1 (0.40) | RARARARBRARGMAPTALDH1A1 | |
| SCHEMBL7662825 | 0.82 | CHRNA7 (0.37) | RARARARBRARGALDH1A1HPGD | |
| SCHEMBL7662818 | 0.82 | CHRNA7 (0.37) | RARARARBRARGALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420363-B1 | Mono- or polyenic carboxylic acid derivatives | EISAI CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| US-6291508-B1 | POTENT ABILITY TO BIND TO RETINOIC ACID RECEPTORS THUS USEFUL IN TREATING PSORIASIS AND RHEUMATOID ARTHRITIS. | EISAI CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |
| WO-2000063140-A1 | TEMPLATE DIRECTED SOLID-STATE ORGANIC SYNTHESIS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2000-10-26 | — | — | WO | disclosed |
| US-6133283-A | Mono- or polyenic carboxylic acid derivatives | EISAI CO., LTD. (JP) | 2000-10-17 | — | — | US | disclosed |
| US-6030964-A | BINDS TO RETINOIC ACID RECEPTORS AND USEFUL FOR TREATING PSORIASIS, AUTOIMMUNE DISEASES, TUMORS, RHEUMATOID ARTHRITIS AND FOR INDUCING IMMUNOSUPPRESSION IN ORGAN TRANSPLANTATION | EISAI CO., LTD. (JP) | 2000-02-29 | — | — | US | disclosed |
| US-5977125-A | Mono-or polyenic carboxylic acid derivatives | EISAI CO., LTD. (JP) | 1999-11-02 | — | — | US | disclosed |