Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 9/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.39 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050662 | 0.88 | RXFP1 (0.51) | RXFP1CCR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL22941300 | 0.84 | KCNQ4 (0.47) | RXFP1MAPTHTTKCNQ4KCNQ5 | |
| SCHEMBL22941720 | 0.83 | CYP1A2 (0.45) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL7509534 | 0.83 | RXFP1 (0.47) | RXFP1CCR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29803126 | 0.82 | RXFP1 (0.53) | RXFP1CCR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18358683 | 0.82 | RXFP1 (0.53) | RXFP1CCR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29803307 | 0.82 | RXFP1 (0.55) | RXFP1CCR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7667607 | 0.82 | RXFP1 (0.55) | RXFP1CCR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7667429 | 0.82 | ALDH1A1 (0.47) | RXFP1CCR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7379044 | 0.81 | RXFP1 (0.43) | RXFP1CCR2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179909-B2 | Process for the manufacture of a product of the thiazolo [3,4,5-de] [4,1]benzothiazepine type | AVENTIS PHARMA S.A. (FR) | 2007-02-20 | — | — | US | disclosed |
| US-6369221-B1 | Thiazolobenzoheterocycles, preparation and medicines containing same | AVENTIS PHARMA S.A. (FR) | 2002-04-09 | — | — | US | disclosed |