Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 8/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6134461 | 0.89 | MAPT (0.38) | KMT2ASMN1; SMN2MAPTALDH1A1PPARG | |
| SCHEMBL6299082 | 0.84 | KMT2A (0.44) | KMT2ASMN1; SMN2MAPTALDH1A1PPARG | |
| SCHEMBL6306004 | 0.81 | PPARG (0.41) | KMT2ASMN1; SMN2MAPTALDH1A1PPARG | |
| SCHEMBL6299833 | 0.81 | KMT2A (0.44) | KMT2ASMN1; SMN2MAPTALDH1A1PPARG | |
| SCHEMBL6299297 | 0.80 | MAPT (0.36) | KMT2ASMN1; SMN2MAPTALDH1A1PPARG | |
| SCHEMBL6299210 | 0.79 | MAPT (0.39) | KMT2ASMN1; SMN2MAPTALDH1A1PPARG | |
| SCHEMBL6299858 | 0.79 | CCR2 (0.44) | KMT2ASMN1; SMN2MAPTALDH1A1PPARG | |
| SCHEMBL6305630 | 0.79 | S1PR1 (0.39) | KMT2ASMN1; SMN2MAPTALDH1A1PPARG | |
| SCHEMBL6300478 | 0.79 | MAPT (0.38) | KMT2ASMN1; SMN2MAPTALDH1A1PPARG | |
| SCHEMBL6300476 | 0.79 | MAPT (0.38) | KMT2ASMN1; SMN2MAPTALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348474-B1 | COMPOUNDS AS ANTIDIABETIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-19 | — | — | US | disclosed |