Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667575 | 0.85 | CFTR (0.47) | ALDH1A1KDM4EHPGDHSD17B10PPARA | |
| SCHEMBL7382474 | 0.77 | EPHX1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10CFTR | |
| SCHEMBL7667623 | 0.77 | EPHX1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10CFTR | |
| SCHEMBL7382472 | 0.77 | EPHX1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10CFTR | |
| SCHEMBL3984430 | 0.76 | SLC6A2 (0.40) | ALDH1A1KDM4EHPGDHSD17B10CFTR | |
| SCHEMBL7387757 | 0.75 | RXFP1 (0.45) | ALDH1A1PPARAMEN1MAPTKMT2A | |
| SCHEMBL8369193 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10CFTR | |
| SCHEMBL31429249 | 0.70 | CFTR (0.44) | ALDH1A1KDM4EHPGDHSD17B10CFTR | |
| SCHEMBL4596562 | 0.70 | HDAC2 (0.47) | ALDH1A1KDM4EHPGDHSD17B10PPARA | |
| SCHEMBL1261721 | 0.70 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369221-B1 | Thiazolobenzoheterocycles, preparation and medicines containing same | AVENTIS PHARMA S.A. (FR) | 2002-04-09 | — | — | US | disclosed |