Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | ADA | P00813 | 12/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452599 | 0.84 | CYP4F2 (0.52) | CYP4F2CYP4A11ADAF2F10 | |
| SCHEMBL7669344 | 0.83 | ADA (0.50) | CYP4F2CYP4A11ADAF2F10 | |
| SCHEMBL7669806 | 0.83 | ADA (0.43) | ADA | |
| SCHEMBL6170286 | 0.82 | ADA (0.46) | ADA | |
| SCHEMBL7452591 | 0.81 | ADA (0.66) | CYP4F2CYP4A11ADAF2F10 | |
| SCHEMBL6171963 | 0.77 | ADA (0.46) | ADA | |
| SCHEMBL7451637 | 0.76 | ADA (0.45) | ADAPRSS1 | |
| SCHEMBL6935339 | 0.73 | ADA (0.51) | ADASMN1; SMN2 | |
| SCHEMBL6940904 | 0.73 | ADA (0.42) | ADA | |
| SCHEMBL6933487 | 0.71 | ADA (0.49) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359145-B1 | ADENOSINE DEAMINASE INHIBITOR; ANTIINFLAMMATORY AGENTS; IMMUNOSUPPRESSANT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |