Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 9/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451637 | 0.90 | ADA (0.45) | ADAFAAHGRIK1 | |
| SCHEMBL6170286 | 0.82 | ADA (0.46) | ADA | |
| SCHEMBL6939865 | 0.80 | MEN1 (0.38) | — | |
| SCHEMBL6171958 | 0.79 | ADA (0.56) | ADAPLA2G4A | |
| SCHEMBL6171955 | 0.79 | ADA (0.56) | ADAPLA2G4A | |
| SCHEMBL7669806 | 0.79 | ADA (0.43) | ADA | |
| SCHEMBL6935340 | 0.77 | ADA (0.72) | ADAPLA2G4A | |
| SCHEMBL7669347 | 0.77 | CYP4F2 (0.45) | ADA | |
| SCHEMBL6938571 | 0.76 | ADA (0.71) | ADA | |
| SCHEMBL6941943 | 0.76 | ADA (0.71) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098885-B9 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-05-18 | — | — | EP | disclosed |
| EP-1098885-B1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS ADENOSINE DEAMINASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-6359145-B1 | ADENOSINE DEAMINASE INHIBITOR; ANTIINFLAMMATORY AGENTS; IMMUNOSUPPRESSANT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |