Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665210 | 0.91 | CCR5 (0.62) | CCR5 | |
| SCHEMBL7669546 | 0.89 | CCR5 (0.59) | CCR5 | |
| SCHEMBL7668410 | 0.88 | CCR5 (0.58) | CCR5 | |
| SCHEMBL7666829 | 0.88 | CCR5 (0.58) | CCR5 | |
| SCHEMBL7674353 | 0.88 | CCR5 (0.58) | CCR5 | |
| SCHEMBL7669213 | 0.88 | CCR5 (0.56) | CCR5 | |
| SCHEMBL7666770 | 0.87 | CCR5 (0.63) | CCR5 | |
| SCHEMBL7666771 | 0.87 | CCR5 (0.59) | CCR5 | |
| SCHEMBL7674979 | 0.86 | CCR5 (0.56) | CCR5 | |
| Hydrochloric Acid SCHEMBL7668809 | 0.85 | CCR5 (0.59) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500844-B1 | PIPERIDINYL-1-METHYLCYCLOPENTANES AND STEREOISOMERS, USED AS ANTIINFLAMMATORY AND PROPHYLACTIC AGENTS AGAINST ALLERGIC RHINITIS, DERMATITIS, VISION DEFECTS, ASTHMA, ATHRITIS AND FOR PREVENTION OR DELAY OF AQUIRED IMMUNE DIFICIENCY SYNDROME | MERCK & CO., INC. | 2002-12-31 | — | — | US | disclosed |