Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689852 | 0.92 | TP53 (0.37) | ROCK2TP53LMNAMAPTGRIN1 | |
| SCHEMBL7669141 | 0.90 | TP53 (0.44) | ROCK2TP53LMNAMAPTHPGD | |
| SCHEMBL7667864 | 0.90 | GRIN1 (0.42) | ROCK2TP53LMNAMAPTGRIN1 | |
| SCHEMBL7671615 | 0.89 | HPGD (0.41) | TP53LMNAMAPTHPGDP2RX7 | |
| SCHEMBL7671400 | 0.89 | TP53 (0.41) | TP53LMNAMAPTTHRBHPGD | |
| SCHEMBL7687502 | 0.88 | TP53 (0.39) | ROCK2TP53LMNAMAPTTHRB | |
| SCHEMBL7662211 | 0.85 | GRIN1 (0.38) | ROCK2TP53LMNAMAPTGRIN1 | |
| SCHEMBL7660472 | 0.85 | LMNA (0.41) | ROCK2TP53LMNAMAPTHPGD | |
| SCHEMBL7674096 | 0.85 | KCNH2 (0.38) | ROCK2TP53LMNAMAPTTHRB | |
| SCHEMBL7672496 | 0.85 | TP53 (0.41) | TP53LMNAMAPTGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489487-B1 | AGRICULTURAL OR HORTICULTURAL FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-03 | — | — | US | disclosed |
| EP-1103548-A1 | TRIAZOLONE DERIVATIVES, USE THEREOF, AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-05-30 | — | — | EP | disclosed |