Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | CA4 | P22748 | 2/20 | 0.64 |
| ▸ | CA6 | P23280 | 2/20 | 0.64 |
| ▸ | CA7 | P43166 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CA3 | P07451 | 1/20 | 0.64 |
| ▸ | SELL | P14151 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | SELP | P16109 | 1/20 | 0.64 |
| ▸ | FUT4 | P22083 | 1/20 | 0.64 |
| ▸ | DPP4 | P27487 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12491809 | 0.89 | ERN1 (0.54) | MAPTALDH1A1KDM4ECA12CA1 | |
| SCHEMBL29475526 | 0.84 | ERN1 (0.66) | MAPTALDH1A1KDM4ECA12CA1 | |
| SCHEMBL22465969 | 0.84 | ERN1 (0.66) | MAPTALDH1A1KDM4ECA12CA1 | |
| SCHEMBL21579476 | 0.82 | CA12 (0.61) | MAPTALDH1A1KDM4ECA12CA1 | |
| Gallic Acid SCHEMBL27698025 | 0.80 | CA12 (0.81) | MAPTALDH1A1KDM4ECA12CA1 | |
| SCHEMBL25385602 | 0.80 | TTR (0.67) | MAPTALDH1A1KDM4ECA12CA1 | |
| SCHEMBL30574966 | 0.80 | TTR (0.67) | MAPTALDH1A1KDM4ECA12CA1 | |
| SCHEMBL5648278 | 0.80 | ERN1 (0.50) | MAPTALDH1A1KDM4ECA12CA1 | |
| SCHEMBL31056230 | 0.80 | TTR (0.67) | MAPTALDH1A1KDM4ECA12CA1 | |
| Gallic Acid SCHEMBL1845406 | 0.79 | CA12 (1.00) | MAPTALDH1A1KDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380181-B1 | AMINO ACID RESIDUES IN THE 3-AND/OR 4-POSITION FUNCTION AS SIDEROPHORES AND/OR AS BIOLOGICAL CHELATING AGENTS FOR IRON IN GRAM-NEGATIVE BACTERIA | GRUENENTHAL GMBH (DE) | 2002-04-30 | — | — | US | disclosed |
| EP-0907633-B1 | NEW SYNTHETIC CATECHOL DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF | GRUENENTHAL GMBH (DE) | 2001-08-22 | — | — | EP | disclosed |
| EP-0907633-A1 | NEW SYNTHETIC CATECHOL DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF | Grünenthal GmbH (DE) | 1999-04-14 | — | — | EP | disclosed |
| EP-0584085-B1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997049670-A1 | NEW SYNTHETIC CATECHOL DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF | Grünenthal GmbH (DE) | 1997-12-31 | — | — | WO | disclosed |
| US-5554606-A | THIENAMYCIN DERIVATIVES; PSEUDOMONAS | ZENECA LIMITED (GB) | 1996-09-10 | — | — | US | disclosed |
| EP-0584085-A1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LIMITED (GB) | 1994-03-02 | — | — | EP | disclosed |
| WO-1992017479-A1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LTD. (GB) | 1992-10-15 | — | — | WO | disclosed |
| US-5126444-A | Antibiotics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-30 | — | — | US | disclosed |
| US-5064824-A | CEPHALOSPORIN COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-12 | — | — | US | disclosed |
| EP-0341910-A2 | Cephalosporins, process for their preparation, intermediates and pharmaceutical compositions | ZENECA LIMITED (GB) | 1989-11-15 | — | — | EP | disclosed |