Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 11/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CA3 | P07451 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SELL | P14151 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SELP | P16109 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669530 | 0.89 | MAPT (0.64) | ERN1CA12CA1CA2CA7 | |
| SCHEMBL5648278 | 0.86 | ERN1 (0.50) | ERN1CA12CA1CA2CA7 | |
| SCHEMBL31056230 | 0.86 | TTR (0.67) | ERN1CA12CA1CA2CA7 | |
| SCHEMBL29475526 | 0.86 | ERN1 (0.66) | ERN1CA12CA1CA2CA7 | |
| SCHEMBL22465969 | 0.86 | ERN1 (0.66) | ERN1CA12CA1CA2CA7 | |
| SCHEMBL25385602 | 0.86 | TTR (0.67) | ERN1CA12CA1CA2CA7 | |
| SCHEMBL30574966 | 0.86 | TTR (0.67) | ERN1CA12CA1CA2CA7 | |
| SCHEMBL25385966 | 0.81 | GLRA3 (0.50) | ERN1ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL15813536 | 0.81 | CA12 (0.70) | ERN1CA12CA1CA2CA7 | |
| SCHEMBL14953740 | 0.81 | CYP19A1 (0.49) | ERN1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11673100-B2 | Systems and methods for integrated solar photodialysis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-13 | — | — | US | disclosed |
| US-11673100-B2 | Systems and methods for integrated solar photodialysis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-13 | — | — | US | disclosed |
| US-11318424-B2 | Light-driven ion-pumping membrane systems | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-05-03 | — | — | US | disclosed |
| US-20190217255-A1 | SYSTEMS AND METHODS FOR INTEGRATED SOLAR PHOTODIALYSIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-07-18 | — | — | US | disclosed |
| EP-2686385-B1 | ACTIVATABLE FLUOROGENIC COMPOUNDS AND USES THEREOF AS NEAR INFRARED PROBES | UNIV RAMOT (IL) | 2019-01-16 | — | — | EP | disclosed |
| EP-2686385-B1 | ACTIVATABLE FLUOROGENIC COMPOUNDS AND USES THEREOF AS NEAR INFRARED PROBES | UNIV RAMOT (IL) | 2019-01-16 | — | — | EP | disclosed |
| US-10071983-B2 | Activatable fluorogenic compounds and uses thereof as near infrared probes | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2018-09-11 | — | — | US | disclosed |
| CN-108218803-A | A kind of method of hexa-atomic imines cycle compound and the hexa-atomic imines cycle compound of one pot process | 首都医科大学 | 2018-06-29 | — | — | CN | disclosed |
| US-20180065095-A1 | LIGHT-DRIVEN ION-PUMPING MEMBRANE SYSTEMS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-03-08 | — | — | US | disclosed |
| US-20180065095-A1 | LIGHT-DRIVEN ION-PUMPING MEMBRANE SYSTEMS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-03-08 | — | — | US | disclosed |
| US-20160229840-A1 | ACTIVATABLE FLUOROGENIC COMPOUNDS AND USES THEREOF AS NEAR INFRARED PROBES | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-08-11 | — | — | US | disclosed |
| US-20160229840-A1 | ACTIVATABLE FLUOROGENIC COMPOUNDS AND USES THEREOF AS NEAR INFRARED PROBES | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-08-11 | — | — | US | disclosed |
| US-20160229840-A1 | ACTIVATABLE FLUOROGENIC COMPOUNDS AND USES THEREOF AS NEAR INFRARED PROBES | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-08-11 | — | — | US | disclosed |
| US-9341630-B2 | Activatable fluorogenic compounds and uses thereof as near infrared probes | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-05-17 | — | — | US | disclosed |
| US-9341630-B2 | Activatable fluorogenic compounds and uses thereof as near infrared probes | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-05-17 | — | — | US | disclosed |
| US-9341630-B2 | Activatable fluorogenic compounds and uses thereof as near infrared probes | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2016-05-17 | — | — | US | disclosed |
| EP-2686385-A2 | ACTIVATABLE FLUOROGENIC COMPOUNDS AND USES THEREOF AS NEAR INFRARED PROBES | Ramot at Tel Aviv University, Ltd. (IL) | 2014-01-22 | — | — | EP | disclosed |
| WO-2012123916-A2 | ACTIVATABLE FLUOROGENIC COMPOUNDS AND USES THEREOF AS NEAR INFRARED PROBES | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-09-20 | — | — | WO | disclosed |
| WO-2012123916-A2 | ACTIVATABLE FLUOROGENIC COMPOUNDS AND USES THEREOF AS NEAR INFRARED PROBES | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2012-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229840-A1 | ACTIVATABLE FLUOROGENIC COMPOUNDS AND USES THEREOF AS NEAR INFRARED PROBES | PAICS, NQO1, APEX1 | ERN1 2602/4885CA12 516/4885CA1 296/4885 |
| US-10071983-B2 | Activatable fluorogenic compounds and uses thereof as near infrared probes | PAICS, NQO1, APEX1 | ERN1 2602/4885CA12 516/4885CA1 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.