Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.68 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.60 |
| ▸ | TUBB | P07437 | 1/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | CNR2 | P34972 | 1/20 | 0.60 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671445 | 1.00 | ESR1 (0.68) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL6962321 | 1.00 | ESR1 (0.68) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL7667665 | 1.00 | ESR1 (0.68) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL7671512 | 0.99 | ESR1 (0.69) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL7665777 | 0.97 | ESR1 (0.69) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL23113126 | 0.94 | ESR1 (0.70) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL6973749 | 0.92 | ESR1 (0.68) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL6967393 | 0.90 | ESR1 (0.71) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL7970907 | 0.89 | ESR1 (0.73) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL6980679 | 0.88 | ESR1 (0.71) | ESR1ESR2TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432983-B1 | Benzothiophene compounds intermediates processes and methods of use | ELI LILLY AND COMPANY | 2002-08-13 | — | — | US | disclosed |
| EP-0816360-A1 | Benzothiophene compounds, intermediates, processes, and methods of use | ELI LILLY AND COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |