Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670041 | 1.00 | NPC1 (0.47) | NPC1RAB9ACYP2C9MEN1KMT2A | |
| SCHEMBL10895608 | 0.96 | NPC1 (0.44) | NPC1RAB9ACYP2C9MEN1KMT2A | |
| SCHEMBL10895598 | 0.96 | NPC1 (0.44) | NPC1RAB9ACYP2C9MEN1KMT2A | |
| SCHEMBL10895614 | 0.96 | NPC1 (0.44) | NPC1RAB9ACYP2C9MEN1KMT2A | |
| SCHEMBL29201213 | 0.95 | NPC1 (0.49) | NPC1RAB9ACYP2C9MEN1KMT2A | |
| SCHEMBL4803851 | 0.94 | CYP2C9 (0.50) | CYP2C9MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL4803860 | 0.94 | CYP2C9 (0.50) | CYP2C9MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11191523 | 0.92 | SPHK1 (0.50) | CYP2C9MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11190738 | 0.92 | SPHK1 (0.50) | CYP2C9MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11198137 | 0.92 | SPHK1 (0.50) | CYP2C9MEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6388146-B1 | AROMATIC UNSATURATED NOMONER | SHARP KABUSHIKI KAISHA (JP) | 2002-05-14 | — | — | US | disclosed |
| US-6074708-A | Photoinitiator photopolymerizable resin composition, polymer and liquid crystal display device | SHARP KABUSHIKI KAISHA (JP) | 2000-06-13 | — | — | US | disclosed |
| EP-0532511-B1 | TRETRA-SUBSTITUTED METHANES WITH LIQUID CRYSTAL PROPERTIES | CONSORTIUM ELEKTROCHEM IND (DE) | 1994-11-02 | — | — | EP | disclosed |
| US-5326495-A | Tetrasubstituted methanes having liquid-crystalline properties | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1994-07-05 | — | — | US | disclosed |
| WO-1991016295-A1 | TRETRA-SUBSTITUTED METHANES WITH LIQUID CRYSTAL PROPERTIES | Consortium für elektrochemische Industrie GmbH (DE) | 1991-10-31 | — | — | WO | disclosed |
| US-5045229-A | Liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-09-03 | — | — | US | disclosed |
| EP-0087963-B1 | PHTHALONITRILE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | Hitachi, Ltd. (JP) | 1989-05-03 | — | — | EP | disclosed |
| US-4545922-A | Liquid crystalline fluorine-containing cyclohexylbiphenyls and dielectrics and electro-optical display elements based thereon | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-10-08 | — | — | US | disclosed |
| EP-0074608-B1 | LIQUID CRYSTAL HALOGEN COMPOUNDS, PROCESS FOR THEIR PREPARATION, DIELECTRIC AND DECTROOPTICAL DISPLAY ELEMENT CONTAINING THEM | MERCK PATENT GmbH (DE) | 1985-07-03 | — | — | EP | disclosed |
| US-4490305-A | Liquid-crystalline halogen compounds, process for their preparation, dielectrics containing these, and electro-optical display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-12-25 | — | — | US | disclosed |
| US-4479885-A | Phthalonitrile derivatives and a liquid crystal composition containing the same | HITACHI, LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0051738-B1 | CYCLOHEXYL-BIPHENYL DERIVATIVES THAT CONTAIN FLUOR, DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL INDICATING ELEMENT | MERCK PATENT GmbH (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-4415470-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-11-15 | — | — | US | disclosed |
| EP-0087963-A2 | Phthalonitrile derivatives and liquid crystal compositions containing them | Hitachi, Ltd. (JP) | 1983-09-07 | — | — | EP | disclosed |
| EP-0030277-B1 | PARTIALLY HYDROGENATED OLIGO-1,4-PHENYLENES, DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL INDICATING DEVICE | MERCK PATENT GmbH (DE) | 1983-07-27 | — | — | EP | disclosed |
| EP-0074608-A2 | Liquid crystal halogen compounds, process for their preparation, dielectric and dectrooptical display element containing them | MERCK PATENT GmbH (DE) | 1983-03-23 | — | — | EP | disclosed |
| US-4331552-A | Liquid crystalline, partially hydrogenated oligo-1,4-phenylenes and dielectrics and electro-optical display elements containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-05-25 | — | — | US | disclosed |
| EP-0051738-A1 | Cyclohexyl-biphenyl derivatives that contain fluor, dielectrics containing them and electro-optical indicating element | MERCK PATENT GmbH (DE) | 1982-05-19 | — | — | EP | disclosed |
| EP-0030277-A1 | Partially hydrogenated oligo-1,4-phenylenes, dielectrics containing them and electro-optical indicating device | MERCK PATENT GmbH (DE) | 1981-06-17 | — | — | EP | disclosed |
| US-4154697-A | Liquid crystalline hexahydroterphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1979-05-15 | — | — | US | disclosed |