SCHEMBL7670041

SCHEMBL7670041

CCCCCC1CCC(c2ccc(-c3ccccc3)cc2)CC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
CYP2C9 P11712 2/20 0.46
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
MAPT P10636 3/20 0.43
MAPK1 P28482 3/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
SPHK1 Q9NYA1 6/20 0.43
GAA P10253 3/20 0.42
ESR2 Q92731 1/20 0.41
DRD2 P14416 1/20 0.41
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
CYP2C19 P33261 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
SPHK2 Q9NRA0 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7670032 1.00 NPC1 (0.47) NPC1RAB9ACYP2C9MEN1KMT2A
SCHEMBL10895608 0.96 NPC1 (0.44) NPC1RAB9ACYP2C9MEN1KMT2A
SCHEMBL10895598 0.96 NPC1 (0.44) NPC1RAB9ACYP2C9MEN1KMT2A
SCHEMBL10895614 0.96 NPC1 (0.44) NPC1RAB9ACYP2C9MEN1KMT2A
SCHEMBL29201213 0.95 NPC1 (0.49) NPC1RAB9ACYP2C9MEN1KMT2A
SCHEMBL4803851 0.94 CYP2C9 (0.50) CYP2C9MEN1KMT2AMAPTMAPK1
SCHEMBL4803860 0.94 CYP2C9 (0.50) CYP2C9MEN1KMT2AMAPTMAPK1
SCHEMBL11191523 0.92 SPHK1 (0.50) CYP2C9MEN1KMT2AMAPTMAPK1
SCHEMBL11190738 0.92 SPHK1 (0.50) CYP2C9MEN1KMT2AMAPTMAPK1
SCHEMBL11198137 0.92 SPHK1 (0.50) CYP2C9MEN1KMT2AMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116333755-B Liquid crystal compound and composition with high clearing point and low dielectric loss 西安近代化学研究所 2025-02-11 CN disclosed
CN-118434716-A Isothiocyanoethynyl benzene derivatives 默克专利股份有限公司 2024-08-02 CN disclosed
CN-116333755-A Liquid crystal compound and composition with high clearing point and low dielectric loss 西安近代化学研究所 2023-06-27 CN disclosed
CN-113652705-B Method for synthesizing fluorenone through catalytic electrolysis of N-hydroxyphthalimide 北京工业大学 2022-07-22 CN disclosed
CN-101857517-B Method for preparing fluorobiaryl compound in pure water solution UNIV DALIAN TECH 2012-12-26 CN disclosed
CN-101857517-A Method for preparing fluorobiaryl compound in pure water solution UNIV DALIAN TECH 2010-10-13 CN disclosed
US-6388146-B1 AROMATIC UNSATURATED NOMONER SHARP KABUSHIKI KAISHA (JP) 2002-05-14 US disclosed
US-6074708-A Photoinitiator photopolymerizable resin composition, polymer and liquid crystal display device SHARP KABUSHIKI KAISHA (JP) 2000-06-13 US disclosed
US-5045229-A Liquid crystals MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-09-03 US disclosed
EP-0087963-B1 PHTHALONITRILE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM Hitachi, Ltd. (JP) 1989-05-03 EP disclosed
EP-0051738-B1 CYCLOHEXYL-BIPHENYL DERIVATIVES THAT CONTAIN FLUOR, DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL INDICATING ELEMENT MERCK PATENT GmbH (DE) 1984-07-25 EP disclosed
US-4415470-A HIGH SPEED SWITCHING MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-11-15 US disclosed
EP-0087963-A2 Phthalonitrile derivatives and liquid crystal compositions containing them Hitachi, Ltd. (JP) 1983-09-07 EP disclosed
EP-0030277-B1 PARTIALLY HYDROGENATED OLIGO-1,4-PHENYLENES, DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL INDICATING DEVICE MERCK PATENT GmbH (DE) 1983-07-27 EP disclosed
EP-0074608-A2 Liquid crystal halogen compounds, process for their preparation, dielectric and dectrooptical display element containing them MERCK PATENT GmbH (DE) 1983-03-23 EP disclosed
EP-0022183-B1 DERIVATIVES OF CYCLOHEXYLBIPHENYL, PROCESS FOR THEIR PREPARATION, DIELECTRICS CONTAINING THEM, AND ELECTRON OPTICAL INDICATING ELEMENTS MERCK PATENT GmbH (DE) 1982-06-23 EP disclosed
US-4331552-A Liquid crystalline, partially hydrogenated oligo-1,4-phenylenes and dielectrics and electro-optical display elements containing them MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-05-25 US disclosed
EP-0051738-A1 Cyclohexyl-biphenyl derivatives that contain fluor, dielectrics containing them and electro-optical indicating element MERCK PATENT GmbH (DE) 1982-05-19 EP disclosed
US-4330426-A Cyclohexylbiphenyls, their preparation and use in dielectrics and electrooptical display elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-05-18 US disclosed
EP-0022183-A2 Derivatives of cyclohexylbiphenyl, process for their preparation, dielectrics containing them, and electron optical indicating elements MERCK PATENT GmbH (DE) 1981-01-14 EP disclosed