SCHEMBL7670107

SCHEMBL7670107

C#CCN1C(=O)COc2cc(F)c(-c3nn4c(c3Cl)CCCC4)cc21

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGFR P00533 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9385152 0.89 EGFR (0.34) EGFR
SCHEMBL6911403 0.79 SLC5A1 (0.33) EGFR
SCHEMBL8570945 0.75 SLC5A1 (0.33) EGFR
SCHEMBL6719202 0.75 EGFR (0.34) EGFR
SCHEMBL26001241 0.75 DRD2 (0.37) EGFR
SCHEMBL16063458 0.74 EGFR (0.34) EGFR
SCHEMBL25359353 0.74 CHRM1 (0.35)
SCHEMBL30194045 0.74 CHRM1 (0.35)
SCHEMBL16063579 0.74 EGFR (0.35) EGFR
SCHEMBL26830858 0.73 HTT (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358885-B1 PREEMERGENT OR POSTEMERGENT HERBICIDES OR PLANT GROWTH REGULANTS MISSISSIPPI STATE UNIVERSITY 2002-03-19 US disclosed
US-5977028-A Substituted phenylheterocyclic herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-11-02 US disclosed
EP-0626962-B1 SUBSTITUTED PHENYLHETEROCYCLIC HERBICIDES DU PONT (US) 1999-03-17 EP disclosed
US-5670455-A Substituted phenylheterocyclic herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-09-23 US disclosed
EP-0626962-A1 SUBSTITUTED PHENYLHETEROCYCLIC HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-12-07 EP disclosed
WO-1993015074-A1 SUBSTITUTED PHENYLHETEROCYCLIC HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-08-05 WO disclosed