Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662016 | 0.86 | CHRNB2 (0.54) | CHRNA7CHRNB2CHRNA4HTTSMN1; SMN2 | |
| SCHEMBL7670727 | 0.76 | CHRNA7 (0.50) | CHRNA7CHRNB2CHRNA4HTTSMN1; SMN2 | |
| SCHEMBL7669732 | 0.76 | CHRNB2 (0.47) | CHRNA7CHRNB2CHRNA4HTTSMN1; SMN2 | |
| SCHEMBL7669729 | 0.76 | CHRNB2 (0.43) | CHRNA7CHRNB2CHRNA4HTTSMN1; SMN2 | |
| SCHEMBL7670648 | 0.75 | CHRNB2 (0.53) | CHRNB2CHRNA4HTTSMN1; SMN2TDP1 | |
| SCHEMBL7668729 | 0.75 | KMT2A (0.48) | CHRNB2CHRNA4HTTSMN1; SMN2 | |
| SCHEMBL15095828 | 0.75 | CHRNA7 (0.65) | CHRNA7CHRNB2CHRNA4TDP1L3MBTL1 | |
| SCHEMBL7670906 | 0.74 | CHRNB2 (0.46) | CHRNA7CHRNB2CHRNA4HTTSMN1; SMN2 | |
| SCHEMBL7670900 | 0.74 | CHRNB2 (0.46) | CHRNA7CHRNB2CHRNA4HTTSMN1; SMN2 | |
| SCHEMBL10518385 | 0.74 | TDP1 (0.48) | CHRNA7CHRNB2CHRNA4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407248-B1 | INSECTICIDES, MITICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-06-18 | — | — | US | disclosed |
| US-6124297-A | COMBATTING INSECTS OR MITES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-26 | — | — | US | disclosed |
| US-5935981-A | INSECTICIDAL/MITICIDAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5849768-A | α-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0529680-B1 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-05-13 | — | — | EP | disclosed |
| EP-0302389-B1 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5214152-A | Insecticides, miticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0529680-A2 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5175301-A | Insecticide, miticide, pesticide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| EP-0509559-A2 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-21 | — | — | EP | disclosed |
| EP-0302389-A2 | Alpha-unsaturated amines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-08 | — | — | EP | disclosed |